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Vidrava Technologies executes high-throughput bioinformatics workflows, in silico molecular modeling, and certified cell-line assays for oncology research, clinical multi-omics, and sustainable agricultural biotechnology.
Connect directly with our computational genomics and wet-lab specialists in Bangalore to discuss study designs and standard operating procedures.
Modular services tailored for pharmaceutical enterprises, academic consortia, and clinical diagnostic laboratories requiring deterministic computational execution and experimental validation.
Standardized Nextflow execution of Whole Genome (WGS), Whole Exome (WES), and transcriptomic RNA-Seq datasets with comprehensive variant calling.
Structural modeling and graph neural networks trained to simulate protein–ligand binding kinetics, off-target toxicity, and ADMET pharmacokinetic profiles.
GLP-compliant wet-lab validation assays including cancer cell cytotoxicity, real-time RT-qPCR gene expression, and microbiological characterization in Bangalore.
Connected biosensors and field microclimate gateways analyzing soil microbial dynamics, nutrient depletion, and automated irrigation triggers.
Statistical genetics and machine learning pipelines transforming large-scale multi-omics repositories into actionable biological intelligence.
Custom web platforms, Laboratory Information Management Systems, and secure cloud portals engineered for scientific research collaboration.
Every sequencing cohort and validation assay moves through a deterministic workflow with explicit quality thresholds, automated containerized execution, and documentation.
Nucleic Acid Verification
Rigorous sample intake checking concentration, integrity (DIN/RIN ≥ 7.0), and A260/A280 purity prior to library preparation.
FASTQ / BAM Alignment
Adapter trimming with fastp, distributed alignment against GRCh38.p14 via STAR and BWA-MEM with Picard duplicate marking.
GATK 4 Somatic Identification
Identification of single nucleotide variants (SNVs), structural indels, and annotation against ClinVar, gnomAD, and COSMIC.
Certified Validation Testing
Cellular MTT cytotoxicity assays, RT-qPCR gene expression, and IC50 dose-response verification in our Bangalore facility.
Standardized parameters for our primary computational pipelines and wet-lab analytical assays.
| Assay / Pipeline Protocol | Input Requirement | Instrumentation / Pipeline | Standard Deliverables | Standard SLA |
|---|---|---|---|---|
Whole Exome Sequencing (WES) High-Confidence Somatic & Germline | ≥ 500 ng gDNA, A260/A280 ≥ 1.8 | NovaSeq 6000 • GATK 4.5 | Trimmed FASTQ, BAM Index, VCF (SNVs/InDels), QC Report | 5–7 Business Days |
RNA-Seq Transcriptomics Differential Gene Expression & GSEA | ≥ 1 µg Total RNA, RIN ≥ 7.0 | STAR Align • DESeq2 • Bioconductor | Gene Counts Matrix, Normalized FPKM, Volcano Plots, GSEA | 5 Business Days |
In Vitro MTT Cytotoxicity Assay Cancer Cell Viability Screening | Mammalian Cell Lines or Compounds | Microplate Spectrophotometer (570nm) | Dose-Response IC50 Curves, Microphotographs, ANOVA | 4 Business Days |
Target Expression RT-qPCR Relative Quantification (ΔΔCt) | ≥ 500 ng Purified Total RNA | Applied Biosystems QuantStudio 5 | Ct Cycle Worksheets, Replicate Concordance, Fold Changes | 3–5 Business Days |
16S Metagenomics Profiling Microbial Taxonomic Diversity | ≥ 200 ng Environmental DNA | DADA2 • QIIME 2 Architecture | OTU/ASV Tables, Alpha/Beta Diversity, Dendrograms | 6 Business Days |
“Vidrava Technologies delivered an exceptional digital and scientific engineering solution. Their professionalism, technical precision, and domain competence in biotechnology exceeded our expectations.”
Founder, K2VR Analytical Research Pvt Ltd
Our computational biologists and wet-lab scientists in Bangalore are available to evaluate project specifications, review sample requirements, and execute mutual NDAs.